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Tips from an insider: Five innovative tech startups

Tips from an insider: Stockholm tech start-ups

5 hot life science firms in Stockholm

Stockholm's top five infrastructure projects

Four Stockholm-based ICT firms to watch

Stockholm pioneers life science research

ICT startups offer investment opportunity

Swedish companies ready for exit

Five med-tech investment opportunities

Six cleantech investment opportunities

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Sweden tops English-language skills ranking

Sweden ranked world's best country to grow old

Swedish passport world's best for travellers

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Stockholm climbs in competitiveness rankings

Sweden among best countries to be born

Fortune: 'Stockholm top place for startups'

Sweden tops first global Web Index

Sweden world's second most innovative country

Stockholm world's 6th 'best city'

'Cool Stockholm' most competitive Nordic capital

Sweden has (second) best reputation in the world

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Sweden scores highest in 'Rule of law index'

Stockholm world's No1 in intellectual capital

Sweden the world's most ICT-competitive country

Sweden great place for moms – but Norway better

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Sweden’s 10 greenest brands

‘Sweden needs to sell itself more’

Sweden overtakes the US in competitiveness

Sweden 10th ‘most admired country globally’

Sweden climbs in 'doing business' ranking

Sweden among world's least corrupt nations

Sweden's mortality rates world's second lowest

Sweden a good place to die – but Britain is best

Children in Sweden have best lives

Sweden the most competitive EU nation

Safe to do business with Swedes

How Sweden became an innovation frontrunner

Nordic countries world's most food-secure

Sweden the world’s best country – politically

Swedish firms among world's top brands

Swedish brands climb in global ranking

Sweden tops government ranking - while US lags 

'Swedish model' outranks 'American dream'  

Sweden among world's least corrupt nations

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Human Protein Atlas -- Stockholm researchers open the door to unique science map

After more than a decade of research, the world's largest atlas of human proteins has been launched in Stockholm, which scientists say has the potential for new breakthroughs in the pharmaceutical industry. The Human Protein Atlas – managed by researchers from KTH Royal Institute of Technology in the Swedish capital – presents 13 million high resolution images of the human body's building blocks, proteins.


The results immediately gained international attention and served as further confirmation of Stockholm's reputation as a top life science and research breeding ground.


The Economist wrote that the result will be of "great value to researchers" trying to understand how tissues differ at the molecular level, and will help to explain how cancerous tissues differ from ones that are healthy.


"Knowing which proteins are made in each organ in a healthy individual should make it easier for researchers to zero in on the proteins that malfunction in disease, and so better design new drugs and treatments," the New Scientists wrote.


Academic journals like Nature and Science has also highlighted the findings.


The discovery is of great importance for the pharmaceutical industry, according to the university. Today, most drugs on the market work by altering proteins. That means the mapping of proteins has the potential to be a valuable knowledge resource for future research in medicine and life sciences, and contribute to the development of new drugs and diagnostic tools.


"It really feels like an exciting time to launch this knowledge resource for the scientific community with detailed lists of the proteins found in different parts of the human body," said Mathias Uhlén, professor of microbiology, who led the work.


"The database is completely free with unlimited access to information," he added.


Uhlén told the BBC News website: "If you're interested in the brain or neurological disorders or even degenerative diseases like Alzheimer's obviously it is interesting to know which proteins are elevated in the brain."


The project started 11 years ago, and employs some 100 full-time researchers in Sweden, India, South Korea and China. According to the university, it has taken the equivalent of 1,000 man years to create the virtual microscope.


Proteins perform a vast array of functions within living organisms, including acting as a catalyst for metabolic reactions, replicating DNA, responding to stimuli, and transporting molecules from one location to anotherThe atlas consists of four subparts: normal tissue, cancer, subcellular and cell lines with each subpart containing images and data based on antibody-based proteomics and transcriptomics.


The project is funded by 900 million kronor from the Knut and Alice Wallenberg Foundation, one of the largest Swedish funders of research.



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This article was sponsored by Stockholm Business Region.

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Last Updated (Tuesday, 23 December 2014 08:39)


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